Acanthosis nigricans is a skin condition that typically affects the armpits, groin, and neck. It is characterized by areas of dark, velvety discoloration in body folds and creases, as well as thickened skin.

Children who develop the condition have a higher risk of developing type 2 diabetes, and it can also be brought on by medications like nicotinic acid used to treat hyperlipidemia. Rarely, acanthosis nigricans can be a sign of a cancerous tumor in an internal organ, such as the stomach or liver.


The following have been linked to acanthosis nigricans:

Insulin resistance, which is what ultimately results in type 2 diabetes and is present in the majority of people with acanthosis nigricans.

• Hormonal conditions: People with cysts, hypothyroidism, or issues with the adrenal glands are more likely to develop acanthosis nigricans.

High-dose niacin, birth control pills, prednisone, and other corticosteroids are among the medications and dietary supplements that may contribute to acanthosis nigricans.

Acanthosis nigricans can also develop alongside lymphoma or when a cancerous tumor starts to spread inside an internal organ like the liver, colon, or stomach.

Clinical features

Dense, thick, brown patches of skin with a velvety texture that can appear anywhere but are most frequently found in the folds of the neck, groin, and armpit.

On cutaneous and mucosal surfaces, papillomatosis (various finger-like growths) is frequent.

Skin tags are frequently discovered in and near affected areas.

Pruritis (itching) is a possibility, especially in cases of acanthosis nigricans linked to cancer.

Lesions of acanthosis nigricans can also develop on the esophagus, nasal, laryngeal, and oral mucous membranes.

Use Echinacea lotion to wash the lesion if it has any unpleasant odors.


Skin examinations frequently reveal the presence of acanthosis nigricans; however, additional tests may be required to identify the underlying cause.

· A biopsy

· Blood tests

· X-rays


General measures

Acanthosis nigricans, a weight loss disorder associated with obesity

Diet and medication can be used to treat hyperinsulinemia.

Expel or manage the underlying tumor

In drug-induced acanthosis nigricans, stop using offending medications and supplements.

Homeopathy medicines

Argentum nitricum

Irregular blotches, warty granulations, brown, tense, and hard skin, drawing in skin as from a spider web or dried albuminous substance.

Asenicum album

Skin that is darkly discolored, itchy, burning, swollen, and edematous, as well as dry, rough, scaly, dirty, and shriveled.

Lycopodium clavatum

Skin becomes thick and indurated; varicose veins; nevi; erectile tumors; brown spots; freckles worse on the left side of the face and nose; violent itching; fissured eruptions; dry, rawness in folds; shrunken skin, especially on the palms; premature greying of the hair; dropsies; offensive secretions; viscid and offensive perspiration, especially on the feet and axilla; skin complaints associated with gastrointestinal and


Skin that is blotched, raw, rough, hard, or cracked; skin that is worse in the flexures; chloasma, an herpetic eruption on the lips, around the mouth, and nose; thick crusts on the elbows; ringworm in isolated spots; a ringworm-like eruption every spring; severe itching; itching that is not relieved by scratching; urticaria; indurations from constant pressure with a purple color; hyperid


Unhealthy skin, including dry, scaly skin that suppurates from every injury, freckles, intense itching that is worse at night from the heat of the bed, scratching, and washing, as well as pimple eruption, pustules, cracks, and hangnails, as well as excoriation, especially in folds, and skin disorders following local application. Itching, especially from warmth in the evening, frequently returns in spring in damp weather. Varicose veins ulcer

Thuja occidentalis

Dry skin with brown spots, dirty, hairy skin, brown spots on the hands and arms, freckles and blotches, crippled, brittle, and soft nails, coldness on one side, tearing pain in the glands, enlargement of the glands, eruptions on covered parts, worse after scratching, violent burning and itching from the eruptions, and worsening with cold bathing.

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