Eosinophilia, which is defined as an eosinophil count that is higher than normal, is most frequently an indication of a parasitic infection, an allergic reaction, or cancer.
Blood eosinophilia or tissue eosinophilia refers to elevated eosinophil counts in tissues that are infected or inflamed.
If you have tissue eosinophilia, the amount of eosinophils in your bloodstream is likely to be within normal limits. Tissue eosinophilia may be detected in samples obtained during an exploratory procedure or in samples of specific fluids, such as mucus released from nasal tissues.
Usually as part of a complete blood count, a blood test can be used to identify blood eosinophilia. In adults, eosinophilia is generally defined as having more than 500 eosinophils per microliter of blood; hypereosinophilia is defined as having more than 1,500 eosinophils per microliter of blood and persisting for several months.
Symptoms
If you have eosinophilia, your symptoms may or may not be influenced by the cause of the elevated eosinophil count.1 Symptoms that are frequently experienced by people with eosinophilia include:
- Rash
- Itching
- Infections with parasites can cause diarrhea.
- Asthma
- runny nose, especially when connected to allergies
Causes
Your eosinophil count may be elevated for a variety of reasons, some of which are benign and only need minor medical attention. It is also common for the elevated count to be transitory and to go away on its own without any further medical attention.
- Parasite infectionsTravel history is an important part of the work-up for eosinophilia, although a lack of recent travel does not rule out parasitic infections. Schistosomiasis, trichinosis, strongyloidiasis, and ascariasis are some of the parasite infections that commonly cause eosinophilia worldwide.2 These infections can also be found in the United States.
- Drug reactionsThe most frequent drugs linked to eosinophilia are antibiotics (penicillin, cephalosporins), non-steroidal anti-inflammatory drugs (aspirin, ibuprofen), phenytoin (anti-seizure medication), and allopurinol (used to treat gout). Fortunately, most people won’t experience these reactions.
- Atopy:Asthma, seasonal allergies (also known as allergic rhinitis), and eczema are some of the most common causes of mild to moderate eosinophilia, particularly in children. Similarly, food allergies can also cause elevated eosinophil counts. Atopy is a particular reaction that occurs in the body. It is not uncommon for someone to have more than one of these medical conditions as they are related.
- Eosinophils spreading to the esophagus, which ordinarily does not contain eosinophils, is the hallmark of the condition known as **Eosinophilic Esophagitis (**EoE), which affects about 50% of those who have it.4
- Hypereosinophilic Syndromes:Skin, lung, and gastrointestinal tract are frequently affected by hypereosinophilic syndromes (HES), a group of disorders that can be primary (also known as neoplastic), secondary (also known as reactive), or idiopathic (cause unknown) and are characterized by extremely high eosinophil counts and evidence of organ damage from a large number of eosinophils.5
- Churg-Strauss SyndromeChurg-Stauss vasculitis, now known as eosinophilic granulomatosis with polyangiitis, can result in eosinophilia.6 Those who have this condition initially have lung problems like asthma and other respiratory problems, then they eventually develop eosinophilia and vasculitis, an inflammation of the blood vessels.
- Multiple myeloproliferative neoplasms (such as essential thrombocythemia, polycythemia vera), B-cell and T-cell lymphomas, as well as adenocarcinomas of the gastrointestinal tract, lung, and cervix, are known to cause an increase in the eosinophil count.1 These cancers include a rare type of acute myeloid leukemia (AML) called eosinophil
Diagnosis
Eosinophils, one of the white blood cells, are found in the part of the complete blood count (CBC) called the differential, which shows how many of each type of white blood cell (neutrophil, lymphocyte, monocyte, eosinophil, and basophil) are present in the blood. Eosinophilia is detected by this test, like most blood disorders.
Eosinophilia can be classified according to the quantity of eosinophils (absolute eosinophil count), and your healthcare provider will begin working on determining the cause after identifying the condition.
Mild: 500 – 1500 cells/mL
Moderate: 1500 – 5000 cells/mL
Severe: > 5000 cells/mL
HOMOEOPATHIC TREATMENT
The selection of the remedy is based on the theory of individualization and symptoms similarity by using a holistic approach, making homeopathy one of the most well-known holistic systems of medicine. This is the only way through which a state of complete health can be regained by removing all the signs and symptoms from which the patient is suffering. Some significant remedies are given below for Eosinophilia symptoms treatment:
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